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The ‘Ten Commandments’ in Adult Congenital Heart Disease Guidelines: Hypertension and renin-angiotensin system blockers are not associated with expression of angiotensin-converting enzyme 2 (ACE2) in the kidney, Population Health Research Institute foundations, Receive exclusive offers and updates from Oxford Academic, New Faculty Positions - Molecular Epidemiology, Endowed Chair and Head, Division of Infectious Diseases & Co-Director, Center for Infectious Diseases, Ramipril reduces CVD by about one-fourth, whereas Vitamin E was ineffective In patients with diabetes, the benefits of Ramipril are enhanced and also protects the kidney, Clopidogrel adds to the benefits of aspirin in ACS, Nine simple modifiable risk factors are associated with >90% of the risk of MI globally, Beta-blockers reduce myocardial infarction but increase strokes and deaths in non-cardiac surgery, Neither Aspirin nor Clonidine reduced cardiovascular death and non-fatal myocardial infarction but Aspirin showed an increase in major bleeding and Clonidine showed an increase in nonfatal cardiac arrest, Clopidogrel + ASA reduces strokes and CV events compared to ASA alone in AF, Telmisartan is as effective as and better tolerated than Ramipril, but combination of the two does not have added benefits, In impaired glucose tolerance or type 2 diabetes, there was no significant impact of insulin glargine or fish oils on cardiovascular events, Global study involving >700 urban and rural communities from low, middle, and high-income countries documenting NCD burden, their risk factors, and the influence of genetic factors, environment, behaviours, health policies, and health systems in the development of chronic diseases and injuries, Program evaluating the polypill on CVD events, Dabigatran is more effective in preventing strokes and safer than warfarin in atrial fibrillation, Global study of risk factors and stroke management, Monitoring troponin after surgery allows detection of 65% of myocardial infarction and >90% of myocardial injuries—both increase mortality. Director, Center for Health Care Research and Policy, CWRU at The MetroHealth System Unique to PHRI, it also has a focus on neglected diseases and neglected populations. The concept of combination therapy is now being further tested in The International Polycap Study (TIPS) program. Newcastle University > Faculty of Medical Sciences > Research > Research Institutes > Population Health Sciences Institute The Population Health Research Institute (PHRI) is Canada’s premiere global health research institute and a world leader in large clinical trials and population studies. Street Address. From medical and health sciences to history and civic design, our experts are actively involved in research, education, and service work related to promoting the health of the public. Our research is truly collaborative: we work with over 60 academic and clinical institutions in South Africa, and elsewhere in Africa and the world. Public health works to protect and improve the health of communities through policy recommendations, health education and outreach, and research for disease detection and injury prevention. Population Health Research Institute | 2,771 seguidores en LinkedIn | PHRI conducts large global RCTs and studies in #CVD, #stroke, #diabetes, perioperative, ACS, and other health research. To achieve this, we bring together leading researchers from different fields, use cutting edge science to improve people’s health, and help to train the next generation of African scientists. Our academic partners are the University of KwaZulu-Natal (UKZN) and University College London. The Population Health Research Institute organises a termly seminar programme made up of internal and external speakers. For permissions, please email: journals.permissions@oup.com. For full access to this pdf, sign in to an existing account, or purchase an annual subscription. Research and response youtube.
The Institute is home to two Departments - Health Services Research and Public Health and Policy. PRI will send you solid, fact-based research on the world’s most pressing population control-related issues. You will get regular updates on global population control, climate change, abortion, and other top news stories! Get the latest news and information from government on COVID-19 in South Africa here. Myocardial injury accounts for the highest proportion of perioperative deaths, No significant difference between off-pump and on-pump CABG, Methylprednisolone did not reduce mortality or perioperative morbidity. This study has described the elements and causes of the epidemiologic and social transitions globally including the varying effects of nutritional inadequacy and excess (including impact of both high and low sodium consumption); of different forms of alcohol and tobacco use and; of different forms of physical activity (recreational and obligatory) on CVD, and diet on health and mortality. Several of PHRI’s global trials, have established the current standards of prevention and treatment in a range of CVD conditions. All rights reserved. We also seek ways to improve diagnosis, prevention and treatment. Senior Research Faculty, Population Health Research Institute and The Center for Healthcare Research and Policy, The MetroHealth System See Profile. By bringing together a multidisciplinary team of leading investigators, and using a range of research methods (probing biologic mechanisms, large randomized clinical trials, varied approaches for epidemiologic studies, new methods to study the environment and societal influences, and assessing health systems) in a large number of countries, PHRI studies inform the causes, prevention, and control of cardiovascular disease (CVD) and non-communicable diseases (NCDs) by developing a comprehensive and multi-pronged knowledge base. Follow Us: Contact Us. The Africa Health Research Institute (AHRI) is a multidisciplinary, independent research institute based across two sites in the province of KwaZulu-Natal, South Africa. The Main Line Health Center for Population Health Research (CPHR) at the Lankenau Institute for Medical Research is a collaboration between Main Line Health and Thomas Jefferson University’s (TJU) College of Population Health. AHRI is based at two sites in KwaZulu-Natal. As a scientific discipline, it adds a holistic perspective that seeks to improve decision-making so as to reduce inequities or disparities in health care delivery.

We focus on opportunities to collaborate with clinical partners to understand real-world health care delivery and health outcomes. Conflict of interest: J.P. is COO of PHRI but has no conflict of interest or personal gain from contents of article. Africa Health Research Institute was formed on October 1, 2016 out of an amalgamation of the KwaZulu-Natal Research Institute for TB-HIV (K-RITH) and Africa Centre for Population Health. These include the primary and secondary prevention of athero-thrombotic CVD, management of acute coronary syndromes, arrhythmia, strokes, and preventing CV complications of surgery (see Table 1). Shipping Address. Together, we conduct research across a diverse range of disciplines, from mental health to medicine, dentistry and social policy. The Main Line Health Center for Population Health Research (CPHR) at the Lankenau Institute for Medical Research is a collaboration between Main Line Health and Thomas Jefferson University’s (TJU) College of Population Health. Get direct access to reliable, in-depth research right now! The County Health Rankings & Roadmaps program is a collaboration between the Robert Wood Johnson Foundation and the University of Wisconsin Population Health Institute. Director, Population Health Research Institute, The MetroHealth System To advance the understanding of population health by being a research and educational partner to Main Line Health, informing and assessing initiatives to improve the health status and quality of life in the communities it serves. PHRI hosts several prestigious lectureships each year, drawing international leaders in cardiology, perioperative care, population health sciences, biostatistics, and more. Over the years, the PHRI has developed unparalleled expertise in epidemiology, population health and clinical trials. Our website uses cookies to deliver an improved browser experience. Our focus is on epidemiology, clinical research and population level intervention research; primarily on prevention, diagnosis and treatment of HIV and TB and related diseases. The Main Line Health Center for Population Health Research (CPHR) at the Lankenau Institute for Medical Research is a collaboration between Main Line Health and Thomas Jefferson University’s (TJU) College of Population Health. 30 Birge Street Hamilton, ON L8L 0A6 Canada. Safety on campus Population Health Research Themes Our institute focuses mainly on chronic diseases and on the prevention of disease through primary care. Population Health Research Institute also has 20 International Fellows who collaborate closely on our research, many of whom trained at PHRI early in their research career and have returned to their home institutions. The 3 Centers within the Population Health Research Institute have had great success in 2019 with over 40 publications in 2019 and over 20 active grants totaling over 18 million dollars to The MetroHealth System. Center for Clinical Informatics Research and Education, Center for Health Care Research and Policy. Indeed, very few organizations in the world can match the Institute’s capacity. The Africa Health Research Institute is committed to working towards the elimination of HIV and TB disease. Other PHRI research has demonstrated that renin–angiotensin system inhibitor drugs prevent major cardiovascular events in people with diabetes; that long-acting basal insulin glargine has a neutral effect on all of the chronic consequences of diabetes; that targeting perfectly normoglycaemic and normotensive HbA1c and blood pressure levels, and adding a fibrate to a statin is not necessary to reduce cardiovascular events in people with diabetes and cardiovascular risk factors; and that Vitamin E, homocysteine lowering with vitamins and omega 3 fatty acid supplements do not reduce cardiovascular outcomes. With data and specimens from the studies described, research continues to discover novel biologic and genetic biomarkers and determinants.

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